The following background data are abstracted from Gideon www.GideonOnline.com and from references 1-2.
Time and Place:
Tick-borne relapsing fever was first described in the United States in 1915 (Colorado).
– Peak incidence is reported during the summer, with 47% of cases from July to August.
– The disease is most common in Arizona, California, Colorado and Oregon.
– Sporadic cases are reported from Idaho, Kansas, Montana, Nebraska, New Mexico, Oklahoma, Texas, Utah, Washington and Wyoming.
– Most cases occur in the Cascade, Rocky Mountain, San Bernadino and Sierra Nevada ranges.
– 40% of cases involve tourists to endemic areas (1977 to 2000).
– Tick-borne relapsing fever is reportable in Arizona, California, Colorado, Idaho, New Mexico, Nevada, Texas, Utah and Washington.
– 450 cases (300 confirmed and 150 probable) were reported by 11 western states during 1977 to January 2000. Only one fatal case was reported during this period – a neonate born to an infected mother.
– 285 cases were reported by California, Colorado, Idaho, Texas and Washington during 1985 to 1996.
The first case of louse-borne infection in the United States during the twentieth century was reported in 1976 – imported from Ethiopia.
Additional geographic notes:
– Washington and Oregon reported 30 cases during 1965 to 1978.
– Colorado reported 2 cases during 1945 to 1976; 3 in 1977.
– Washington reported 24 cases during 1991 to 1994.
– Oregon reported 73 cases during 1964 to 1989; Washington 27; Arizona 74; Texas 25; Idaho 13; New Mexico 15; Oklahoma 2.
– California reported 251 cases during 1921 (state’s first case) to 1941; 173 during 1964 to 1989; 95 during 1978 to 1998 (including 3 to 18 cases yearly during 1985 to 2002). five cases were reported in the Lake Tahoe region in 2005, 3 during the summer of 2006.
– Texas reported 13 cases during 1990 to the first half of 1994.
An American tourist acquired relapsing fever in Israel (1988 publication).
Infecting species:
– Borrelia hermsii (vector Ornithodoros hermsi) and B. coriaceae in the western region
– B. turicatae (vector O. turicatae) in the southwest. There is also evidence for the existence of Borrelia turicatae in Florida. – B. parkeri (vector O. parkeri) in the west
– B. mazzottii (vector O. talaje) in the south.
– B. miyamotoi has been identified in ixodid ticks (Ixodes pacificus) in California (2006 publication)
– B. coriaceae has been identified in Ornithodoros coriaceus, a common parasite of livestock in the western United States.
Prevalence surveys:
1.9% of I. scapularis adults and 0.8% of nymphs in the northeastern United States (Borrelia miyamotoi, 2009 publication)
Notes regarding transmission:
– Ornithodoros hermsi is nocturnal and feeds within 20 to 90 minutes – thus, patients rarely recall the tick bite.
– B. hermsii is maintained in small sylvatic rodents, notably chipmunks (Tamias spp.) and pine squirrels (Tamiascuirus spp.) above 1,000 meters’ elevation.
– Antibodies to Borrelia hermsii are present in 5.4% of big brown bats (Eptesicus fuscus). (Georgia, 2007 publication)
- Borrelia turicatae has been detected in dogs in Texas. (2007 publication)
Notable outbreaks:
All of the following outbreaks were associated with tick (Ornithodoros spp.) infestations of rodent nests in cabins.
1968 – An outbreak was reported in Spokane County, Washington.
1973 – Outbreaks (62 clinical cases, 16 confirmed) were reported in Grand Canyon National Park, Arizona.
1989 – An outbreak (6 cases) was reported in San Bernardino County, California.
1990 to 1991 – Outbreaks (24 cases, 14 confirmed) were reported in Grand Canyon National Park, Arizona. No outbreaks were reported in this area during 1992 to 1999.
1995 – An outbreak (23 family members) was reported among campers in Colorado.
2002 – An outbreak (5 cases) of Borrelia hermsii infection was associated with a cabin in western Montana. Infected ticks (Ornithodoros hermsi) were identified at the time.
2002 – An outbreak was associated with a family gathering in New Mexico.
References:
1. Berger SA. Relapsing fever: Global Status,, 2011. 63 pp, 68 graphs, 174 references. Gideon e-books, http://www.gideononline.com/ebooks/disease/relapsing-fever-global-status/
2. Berger SA. Infectious Diseases of the United States, 2011. 1030 pp, 464 graphs, 8237 references. Gideon e-books, http://www.gideononline.com/ebooks/country/infectious-diseases-of-the-united-states/