The following background data are abstracted from Gideon www.GideonOnline.com and the Gideon e-book series. Primary references avaialable on request.
Time and Place:
Visceral leishmaniasis is most common in the southern region, notably Andalusia, Palma de Mallorca, Valencia and Catalonia.
– Seroprevalence among dogs in this region is lowest during April, peaking during October.
– A restricted focus has been identified in the Piorat region of northeastern Spain.
– A single autochthonous case has been reported from Minorca.
As noted in the following graphs, disease rates have changed little during the past three decades:

Incidence – additional notes:
– 2,028 were hospitalized for leishmaniasis during 1997 to 2008 (0.41 per 100,000 population; 3.35% fatal; 37% HIV-positive)
– 1,180 were hospitalized during 1999 to 2003 (0.4 per 100,000 population)
– 2,028 were hospitalized during 1997 to 2008 (0.41 per 100,000 population)
– 11 cases (0 fatal) were identified among immunocompetent children in southern Madrid during 1994 to 2007.
– 60 deaths were ascribed to leishmaniasis during 1980 to 1994.
Exported cases:
2005 – Three cases were reported among Romanian workers returning from Spain.
2011 (publication year) – A Norwegian child acquired visceral leishmaniasis in Spain.
2012 – An infected dog was imported from Spain into Singapore.
Leishmaniasis and HIV infection:
– 450 cases of HIV/Leishmania coinfection were reported nationwide during 1990 to 1995 (52.4% of the world’s total coinfections); 1,099 during January 1990 to January 2001; 130 during January 2001 to December 2006. 412 during 1996 to 1998; 1,099 as of 2001.
– Spain accounted for 58% of all such coinfections in southwestern Europe during 1990 to 1998.
– 2.49% of AIDS patients in the Madrid region are coinfected with visceral leishmaniasis.
– 228 episodes of visceral leishmaniasis were diagnosed in 155 HIV-infected patients in Valencia and Murcia during 1988 to 2001.
Transmission through sharing of needles by injecting drug abusers has been reported.
– Approximately 30% of IVDA in southern Spain are seropositive.
– Evidence for Leishmania is found in 52% of discarded syringes collected in southern Madrid (1998) and 34% from southwestern Madrid (2000 to 2001).
Leishmania infantum has been identified in some cases of cutaneous and mucosal leishmaniasis
Prevalence surveys:
2.4% of asymptomatic blood donors in Elvissa (Belearic Islands) have been found to have cryptic infection by ELISA – 7.6% by Western blot (2004 publication)
2% of humans, 0.6% of rabbits and 67% of dogs in southeastern Spain (PCR, 2011 publication)
20.5% of wolves (Canis lupus), 14.1% of foxes (Vulpes vulpes), 28.6% of Egyptian mongooses (Herpestes ichneumon), 1 of 4 genets (Geneta geneta), and 1 of 4 Iberian lynxes (Lynx pardinus) (2008 publication)
29.4% of dogs in the Barcelona region (PCR, 2009 publication)
43.8% of kennel dogs in Majorca (PCR, 2010 publication)
19.6% of seronegative blood samples in a canine blood bank (Leishmanial DNA, Barcelona, 2008 publication)
44% of dogs, 26% of feral cats, 39% of pine materns (Martes martes) and 10% of common genets (Genetta genetta) (Mallorca, PCR, 2011 publication)
3.7% of cats in Madrid (2011 publication)
Seroprevalence surveys:
3.1% of blood donors from the Balearic Islands. (Majorca, Formentera, and Minorca, 2008 publication)
4.9% of the general population in Castilla Leon, and 64.0% of HIV-positive patients (1996)
11.5% of children and 52.8% of adults in Alicante, southeastern region are skin test-positive (1997 to 1998)
2% of humans, 0% of rabbits and 7% of dogs in southeastern Spain (2011 publication)
5.25% of dogs in the Madrid area
7.8% of stray dogs in the Madrid region (1996 to 2006)
13% of dogs on Mallorca are infected; 3.7% in northwestern Spain (2004 publication)
30% of dogs in northeastern Spain (2006 publication)
22% of dogs in Crevillente town, Alicante (1999)
13.0% of dogs in the Alpujarras region of southeastern Spain – with highest rates in larger, older dogs which live outdoors (2006)
8.1% of dogs in the Madrid region (2006 to 2007)
5.3% of shelter dogs in central Spain (2010 publication)
3% of cats in Barcelona (2007 publication)
1.29% of cats in Madrid (2005 to 2006)
6.29% of cats in the northeastern Iberian Peninsula and Balearic Islands (2007 publication)
13.2% of cats on Ibiza (2010 publication)
Leishmania infantum has been identified in captive wolves (Canis lupus) in northern Spain (2008 publication)
– Leishmania infantum has been identified in pine materns (Martes martes) and common genets (Genetta genetta) on Mallorca (PCR, 2011 publication)
Vectors:
The vectors in Spain are Phlebotomus (Larroussius) ariasi and Ph. (La.) perniciosus.
References:
1. Berger SA. Infectious Diseases of Spain, 2012. 557 pp, 194 graphs, 2,850 references. Gideon e-books, http://www.gideononline.com/ebooks/country/infectious-diseases-of-spain/
2. Berger SA. Visceral Leishmaniasis: Global Status, 2012. 88 pp, 73 graphs, 832 references. Gideon e-books, http://www.gideononline.com/ebooks/disease/visceral-leishmaniasis-global-status/
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