Archive for the ‘Epidemiology’ Category

Shigellosis in Denmark and Norway

Friday, June 26th, 2009

A recent outbreak related to imported snow peas belies the fact that shigellosis rates in Denmark and Norway have remained consistently low for more than two decades.

Denmark-Shig

Update: reported in ProMED

Viral Gastroenteritis in Italy

Friday, June 26th, 2009

A recent episode in Brescia is the latest of several outbreaks of viral gastroenteritis in Italy. The following background information is abstracted from GIDEON:

Primary references are available on request.

Prevalence surveys:
Adenoviruses account for 7% of pediatric hospitalizations in Rome for diarrhea, Rotavirus 18.2%, Astrovirus 1% (1987 to 1989)
Adenoviruses account for 17.6% of pediatric hospitalizations in Rome for diarrhea, Rotavirus 26.7%, non-polio Enteroviruses 8.5%, Coronaviruses 1.8%, Parvoviruses 0.9% (1985 publication)
Adenoviruses account for 6% of pediatric hospitalizations in Sicily for diarrhea, Rotavirus 25.1%, Astrovirus 7%, Norovirus 18.6% (2003)
Adenoviruses are found in 6.2% of pediatric patients with acute diarrhea (2005)
Noroviruses account for 10.4% of hospitalized pediatric gastroenteritis cases in northern Italy (2002)
Noroviruses were the most frequently involved viruses (23.7%) in sporadic acute diarrhea among hospitalized children and were more common in children >5 years (37%) than in children <5 years (10%). The frequency of Rotavirus, enteric Adenovirus and Astrovirus was 12.2%, 1.6% and 2.4%, respectively. (Brescia, 2007 publication)
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Onions and Outbreaks

Tuesday, June 23rd, 2009

A recent episode of E. coli infection in Ontario belies the fact that onions are only rarely implicated in food-related disease outbreaks. As of June 2009, 8,471 infectious diseases outbreaks have been included in GIDEON. Onions were involved in only seven (0.08%) of these:

1983 – United States – Botulism – 28 – sauteed onions
1996 to 1997 – United States – Hepatitis A – 90 – green onions
1997 – United States – Cryptosporidiosis – 54 – green onions
1998 – United States – Hepatitis A – 43 – green onions
2003 – United States – Hepatitis A – 170 – green onions
2005 – Russia – Yersinia pseudotuberculosis – 33 – cabbage and onion salads.
2006 – United States – E. coli O157 – 99 – either green onions or shredded lettuce

Coccidioidomycosis Acquired by Foreign Travelers

Wednesday, June 10th, 2009

A recent case in Taiwan is the latest of over 20 foreign travelers who have acquired Coccidioidomycosis in Americas. A module in GIDEON maintains a chronology of all instances of travel-related infection (rabies, trypanosomiasis, trichinosis, Lassa fever, gnathostomiasis, melioidosis, etc). The following list is abstracted from the program.

[primary references are available on request]

Year* Country Cases Comment

1975* Finland 1
1976* Switzerland 1
1990 Israel 1
1993 Czech Republic 1
1996* Netherlands 1
1998* Hungary 1
2001 U.K, Finland, New Zealand 3 Associated with public event
2001 Germany 2 Acquired in Costa Rica
2002 India 1 Fatal infection
2003 Israel 1
2008* France 1
2008* Japan 4 Case series
2008* Poland 1
2009* Netherlands 1

* Year of publication (other cases refer to year of occurrence)

Update: Appeared in ProMED

Viral Hepatitis in Pakistan

Tuesday, June 9th, 2009

Reports of a recent outbreak in Sindh question the relative likelihood of various forms of viral hepatitis in Pakistan. The following data are abstracted from GIDEON. One of the modules in GIDEON follows all published prevalence surveys (Ascariasis, Chlamydial infection, Trachoma, Leprosy …) and seroprevalence surveys (HIV infection, Toxoplasmosis, Rubella … etc) – for every infectious disease, in every country.

[primary references available on request]

Viral hepatitis in Pakistan:

Hepatitis A:
Prevalence
4% of acute hepatitis in pregnant women in Karachi
5.4% of acute hepatitis in Lahore.

Seroprevalence:
94% of children by age 5 (Karachi, 1994 publication)
100% of children ages 14 to 15 (Karachi, 2002 to 2004)
40.57% of persons with clinical suspicion of acute hepatitis (2003 to 2004)

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Relapsing Fever in the United States

Friday, June 5th, 2009

Historical:
Tick-borne relapsing fever was first described in the United States in 1915 (Colorado).
- The first case of louse-borne infection in the United States during the twentieth century was reported in 1976 – imported from Ethiopia.

Time and Place:
Peak incidence is reported during the summer, with 47% of cases from July to August.
- The disease is most common in Arizona, California, Colorado and Oregon.
- Sporadic cases are reported from Idaho, Kansas, Montana, Nebraska, New Mexico, Oklahoma, Texas, Utah, Washington and Wyoming.
- Most cases occur in the Cascade, Rocky Mountain, San Bernadino and Sierra Nevada ranges.
- 40% of cases occur in tourists to endemic areas (1977 to 2000).
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Measles in Bulgaria

Wednesday, May 27th, 2009

A recent outbreak in Dulovo belies the fact that measles rates in Bulgaria and surrounding countries have decreased considerably in recent decades. See graph:

measles-bulgaria

We may assume that decreasing rates are the result of excellent vaccine coverage, which currently exceeds 90% for all countries in the region. See graph:
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Rabies in Mexico

Friday, May 22nd, 2009

Reports of two recent cases of in Jalisco underline the fact that rabies is still a problem in this region. Although Mexico has reported 0 to 2 cases yearly since 2000, highest rates in the area are encountered in El Salvador.

rabies-mexico

46 Cases of Swine Flu (H1N1) Reported in 2008; 50 Cases In Humans Reported From 1958 to 2005, According to GIDEON Informatics

Tuesday, May 5th, 2009

Los Angeles, Calif. (PRWEB) May 5, 2009 — The first recorded outbreak of influenza occurred in 1580, according to GIDEON (www.gideononline.com), the online infectious disease database used by medical professionals worldwide. As of 2003, an additional 31 pandemics had been documented, including 21 million deaths estimated from an H1N1 pandemic during 1918 to 1919. From 1958 to 2005, 50 cases of swine influenza virus infection (mostly H1N1) were reported in humans (http://gideononline.com/swineflu).

GIDEON reports that up until 2006, a total of 46 cases of human infection by swine influenza (more…)

Compare diseases, drugs or pathogens

Friday, May 1st, 2009

One of the most important functions of GIDEON is to help users prepare scientific articles, teaching material and other publications (see the Fingerprint case of the month). A new feature now allows users to create custom-designed charts which compare the features of two or more diseases, drugs or pathogens.

For comparison of key clinical and epidemiological features of infectious diseases, in the Diseases tab, click on a disease (step 1 in the image below), and – while holding down the control button – click on other diseases of your choice. Now click on the Compare button (step 2).

Choosing diseases to compare

Choosing diseases to compare

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Swine Flu outbreak coverage

Monday, April 27th, 2009

GIDEON is providing ongoing coverage of the latest outbreak of Swine Influenza (H1N1) in the Worldwide note for Influenza, and relevant affected countries.
If you’re logged in, here’s a direct link.

Update: Read about the historical cases of H1N1 Swine Influenza

Measles – Outbreaks Associated With Imported Cases

Monday, April 13th, 2009

A case imported from India into the United States is the latest in a growing list of cross-border measles episodes. The following is a chronology of notable outbreaks reported during the past decade.

1998 – An outbreak (69 cases, 2 hospitalized, 0 fatal) in Tuvalu was ascribed to introduced cases among workers from Nauru.
1998 – An outbreak (33 cases) was linked to an infected visitor arriving to Alaska, United States from Japan.
1999 – An outbreak (75 confirmed cases) in Australia was traced to an index case from Indonesia.
2000 – Outbreaks (78 cases, total) in Canada were linked to travel in Mexico (6 cases), Bolivia (19 cases) and Belgium (25 cases).
2000 – An outbreak (992 cases, or 57% of all cases for the Americas region) in Haiti was thought to originated with imported cases from the Dominican Republic.
2000 to 2001 – An outbreak (1,062 cases, 0 fatal) was reported in Tanzania among refugees from Burundi.
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